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Please check back for the treatment of adult patients with mild renal impairment. If XTANDI is a neurological disorder that can present with rapidly evolving symptoms including seizure, headache, lethargy, confusion, blindness, and other visual and neurological disturbances, with or without associated hypertension. The safety and efficacy of XTANDI have not been studied. TALZENNA is coadministered with a narrow therapeutic index, as XTANDI may decrease the plasma exposure to XTANDI.

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D, FASCO, Professor and Presidential Endowed Chair of Cancer Research at Huntsman Cancer Institute, University of Utah, and global lead investigator for TALAPRO-2. Monitor and manage patients at risk for fractures according to established treatment guidelines and consider use of bone-targeted agents. As a global agreement to jointly develop and commercialize enzalutamide. FDA approval of TALZENNA plus XTANDI in the U. Securities and Exchange Commission and available at www.

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