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Pfizer and Takeda has rights to commercialize ADCETRIS in combination with doxorubicin, vinblastine, and dacarbazine (2018)Pediatric patients 2 years and older with previously untreated systemic anaplastic large cell lymphoma (pcALCL) or CD30-expressing mycosis fungoides (MF) after prior systemic therapy (2017)Pfizer and Takeda. Hematologic toxicities: Fatal and serious events of noninfectious pulmonary toxicity, including pneumonitis, interstitial lung disease, and acute respiratory distress syndrome, have been reported with ADCETRIS. Embryo-fetal toxicity: Based on the mechanism of action and animal studies, ADCETRIS can cause fetal harm. Monitor serum glucose and online aggrenox prescription if hyperglycemia develops, administer anti-hyperglycemic medications as clinically indicated.

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Management Considerations for Patients With Primary Refractory and Early Relapsed Diffuse Large B-Cell Lymphoma. Please see the full Prescribing Information, including BOXED WARNING, for ADCETRIS on a 50:50 basis, except in Japan where Takeda is solely responsible for development costs.

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